SPI-1005 is an oral form of the drug ebselen. Ebselen is a
molecule designed to mimic the function of a key enzyme
found in the inner ear, glutathione peroxidase (GPx). Regular
use of aminoglycoside antibiotics can cause damaging side
effects in the inner ear. By mimicking the function of GPx, SPI-
1005 may protect the inner ear from damage.
A phase 1b study to test the safety and tolerability of SPI-1005 in people with CF is
This program is sponsored by Sound Pharmaceuticals and partially funded by Cystic
Fibrosis Foundation Therapeutics (CFFT).
Contact us about SPI-1005 >