Lefamulin (XenletaTM) is a compound that interferes with bacteria's ability to make protein, which is required for bacteria to grow. It is available in both oral and intravenouos (IV) formulations. Lefamulin is FDA-approved for the treatment of adults with community-acquired bacterial pneumonia (CABP). It is currently being studied for its safety and pharmacokinetics in fighting infections in people with CF.
A phase 1 study to test the safety and pharmacokinetics of lefamulin in adults with CF is currently underway.
This program is sponsored by Nabriva.
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