Lives unaffected by cystic fibrosis

Clinical Trial Finder

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Clinical trials are listed below.

  • OtherRecruiting Location: Australia

    Does tiotropium bromide lead to bronchodilation in cystic fibrosis? , protocol number ACTRN12605000728639

    Does tiotropium bromide lead to bronchodilation in cystic fibrosis?

    • Age:

      Not Specified

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      Not Specified

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

    Contact us about this clinical Trial >
  • Anti-InfectiveEnrolling Location: Australia

    Evaluation of CF patient perception of symptom improvement following inhaled antibiotic treatment. , protocol number ACTRN12605000602628

    Diagnosis of CF and chronic PA infection (defined as cultures positive for PA for > 6 months, including most recent culture). Have adequate understanding of English to give informed consent and follow study procedures. Patient must have completed their most recent course of TOBI or aerosolized tobramycin solution or any other aerosolized antibiotic at least 28 days prior to study entry. Parent/guardian of children 6 to 13 years old must agree to complete the CFQ-R and Global Rating of Change Questionnaires. Patient's physician must have decided to prescribe a 28 day course of TOBI for treatment of clinical symptoms (increased cough, increased sputum production/chest congestion, decreased exercise tolerance, or decreased appetite).

    • Age:

      6 years - no stated upper limit

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      Not Specified

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • OtherEnrolling Location: Australia

    Effect of a targetted exercise program versus current exercise practice on function, activity and participation of young people with cystic fibrosis: a randomised, controlled trial , protocol number ACTRN12607000612415

    Exercise is a vital component of the physiotherapy management for young people with cystic fibrosis (CF). The overall aim of this research is to strengthen knowledge about best practice exercise programs for this population. This study compares effects of two exercise programs (the current exercise practice versus a novel targeted exercise program). Ultimately, it is expected that with improved exercise programs, young people with CF may have improved body structure and function, and activity and participation levels, leading to enhanced quality of life.

    • Age:

      18-70 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      40% predicted or above

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • BehavioralEnrolling Location: Australia

    Engaging and re-connecting 'at-risk' children with chronic respiratory illness. , protocol number ACTRN12607000515493

    Children with chronic illness sometimes feel disconnected and lonely. In this study we will evaluate the use of a psycho-social intervention program for 'at-risk' children (ie. child with chronic illness, low socio-economic groups) to improve their sense of well-being, adherence to therapies and health outcomes.

    • Age:

      10-15 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      Not Specified

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • BehavioralNot yet recruiting Location: Australia

    Stretching in cystic fibrosis: does it improve the quality of life and measures of kung function. , protocol number ACTRN12608000484347

    Stretching in cystic fibrosis: does it improve the quality of life and measures of kung function.

    • Age:

      18-70 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      >40% or above

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • Anti-InfectiveEnrolling Location: Australia

    A comparative assessment of the clinical impact , protocol number ACTRN12607000349448

    This study is designed to provide vitally needed information on the clinical implications of being infected by a clonal strain of P. aeruginosa and the risk factors for the acquisition of a clonal strain. This new information will provide a rational basis for the need for changes to infection control policies and better outcome predictors for patients infected with clonal strains of P. aeruginosa.

    • Age:

      2-75 years

    • Mutation(s):

      Not specified

    • FEV1% Predicted:

      Not Specified

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • Restore CFTR FunctionCompleted with results Location: USA & Australia

    Phase 3 study of inacaftor in babies who have a CFTR gating mutation , protocol number NCT02725567 VX15-770-124

    This two-part, open label study is taking place at multiple care centers across the US. It will look at the safety and effectiveness of ivacaftor, as well as how the body processes the drug, in babies who have a CFTR gating mutation.

    • Age:

      0 Months to 24 Months

    • Mutation(s):

      One Copy F508del or No Copies F508del

    • FEV1% Predicted:

      No FEV1 Limit

    • Number of Visits:

      8

    • Length of Participation:

      24 weeks

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  • Restore CFTR FunctionCompleted with results Location: Multiple US sites & Australia

    Phase 2 study of VX-440 combination drug in people with cystic fibrosis. , protocol number NCT02951182 VX15-440-101

    This study is taking place at multiple care centres accross the US. It will look at the safety and effectiveness of the drug VX-440 in combination with ivacaftor and/or tezacaftor (VX-661)

    • Age:

      18 years and older

    • Mutation(s):

      homozygous or hetrozygous F508del

    • FEV1% Predicted:

      40 - 90%

    • Number of Visits:

      11

    • Length of Participation:

      57

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  • Restore CFTR FunctionEnrolling Location: Australia

    Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation) (SAPHIRA1) , protocol number NCT02707562

    A Phase IIa, Open-label Study of Multiple Doses of GLPG1837 in Subjects With Cystic Fibrosis and the G551D Mutation

    • Age:

      >18 years

    • Mutation(s):

      G551D

    • FEV1% Predicted:

      Pre- or post-bronchodilator FEV1 ≥ 40% of predicted normal

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

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  • Restore CFTR FunctionCompleted with results Location: Australia

    A Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects With CF, Homozygous for the F508del-CFTR Mutation , protocol number NCT02514473 VX14-809-109

    A Phase 3, Double Blind, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects Aged 6 Through 11 Years With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

    • Age:

      6-11 years

    • Mutation(s):

      homozygous for the F508del CFTR mutation

    • FEV1% Predicted:

      ppFEV1 of ≥70 p

    • Number of Visits:

      Not specified

    • Length of Participation:

      Not Specified

    Contact us about this clinical Trial >
  • Displaying results 41-50 (of 172)
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