Cystic Fibrosis organisations in Australia provide support and services to people with Cystic Fibrosis (CF) and their carers and families. This is complemented by a commitment to research and a quality improvement program focussing on improved clinical care for people with CF.
Every four days a baby is born in Australia with cystic fibrosis (CF) and more than one million Australians are carriers of cystic fibrosis. Cystic Fibrosis Australia (CFA) is committed to improving clinical practice and patient outcomes through its quality improvement programmes and research with the aim of extending life expectancy from 37 to 50 years by 2025.
Cystic Fibrosis is a recessive genetic condition. It primarily affects the lungs and digestive system because of a malfunction in the exocrine system, responsible for producing saliva, sweat, tears and mucus.
In addition to working for a cure, Cystic Fibrosis Australia also provides support and advocacy to improve the lives of people with cystic fibrosis. Get involved by raising awareness about CF, participating in a fundraising event or volunteering.
Cystic Fibrosis Australia has established a consistent approach to advocacy across Australia and is now a subject matter expert for government, industry and the media.
The Australian Cystic Fibrosis Research Trust (ACFRT) is managed by Cystic Fibrosis Australia (CFA). Since 1989 it has funded more than 300 projects valued at over $6,000,000.
Visit the media room to browse through number of resources including media representatives, press releases and reports.
Clinical trials are listed below.
Mucociliary ClearanceCompleted with results
SHIP: Study of hypertonic saline in preschoolers
, protocol number NCT02378467 SHIP01
This SHIP study evaluated the safety and effectiveness of hypertonic saline (7%) in pre-school children with CF.
3 Years to 5 Years
No Mutation Requirement
Less than 99%
Number of Visits:
Length of Participation:
Anti-InflammatoryCompleted with results
Phase 2 Study of inhaled Alpha-1 HC in people with CF
, protocol number Grifols T6005-201
This study took place at multiple care centres across the US. It looked at the safety and tolerability of inhaled Alpha-1 HC administered once a day for three weeks in people with CF.
18 Years and Older
40 to 90%
Phase 2 Study of Inhaled Nitric Oxide in People with CF
, protocol number NCT02498535
This study is taking place at multiple care centres across the US. It will look at the effectiveness of the inhaled drug nitric oxide in adults with cystic fibrosis who are taking an inhaled antibiotic.
18 years and older
No mutation requirement
Nutritional-GICompleted with results
Phase 2 study of oral glutathione in children with cystic fibrosis.
, protocol number GROW-IP-16 NCT03020719
This study evaluated the safety and effectiveness of the oral drug glutathione in children with cystic fibrosis who use pancreatic enzyme replacement therapy (PERT).
24 months - 10 years
No FEV1 limit
Vitamin D for enhancing the immune system in people with CF
, protocol number NCT01426256 TANGPR11A0
This study evaluated the effect of a single high-dose of vitamin D3 given at the start of a pulmonary exacerbation followed by vitamin D3 maintenance treatment in adults with CF.
16 Years and Older
20% or greater
TEACH: Testing the effect of adding oral azithromycin to inhaled tobramycin in people with CF
, protocol number TEACH-IP-15
This phase 2 study is taking place at multiple care centers across the US. It will look at the effect of adding oral azithromycin to inhaled tobramycin and will use placebo control.
12 Years and Older
25 to 100%
Anti-InfectiveCompleted with results
Arikace compared to Tobi® in people with CF with chronic Pseudomonas aueruginosa infections
, protocol number NCT01315678 Insmed TR02-108
This study looked at the effectiveness, safety and tolerability of Arikayce compared to a currently available antibiotic, TOBI (tobramycin inhalation solution). This study was for people with CF with chronic lung infections.
6 Years and Older
25% or greater
Efficacy and Safety of Ultrase MT20 in Children with CF and Pancreatic Insufficiency
, protocol number Axcan UMT20CF07-01
This study looked at the effectiveness and safety of pancrelipase (ULTRASE MT20) in children who have CF and pancreatic insufficiency.
7 Years to 11 Years
No FEV1 Limit
Use of Utrase MT 12 Enzymes in Young Children with CF Related Pancreatic Insufficiency
, protocol number Axcan UMT12CF08-01
This study evaluated the safety and effectiveness of pancrelipase (Ultrase MT 12) in young children with CF.
2 Years to 6 Years
Restore CFTR FunctionClosed to enrollment
Phase 3 study of lumacaftor and ivacaftor in children with CF
, protocol number Vertex VX13-809-011a
This study is taking place at multiple care centers across the U.S. It looked at the safety of lumacaftor in combination with ivacaftor, as well as how the body processes the drugs, in children with CF.
6 Years to 11 Years
Two copies F508del