Lives unaffected by cystic fibrosis

Reproductive Tract Female

For females living with cystic fibrosis (CF), the thickening of cervical mucus can prevent the movement of sperm across the cervix, leading to fertility problems.

Ovulation and fertility are also affected by the general changes in the body caused by CF symptoms, for example breathing problems and low nutrition. These problems can often be addressed through lifestyle and available CF medicines.

For this reason, females living with CF are usually able to conceive and bear children, having a much lower overall rate of infertility than males living with CF.

Since the CF Community has had access to CFTR modulators we have seen an increase in women with CF having babies.

https://www.cff.org/Life-With-CF/Transitions/Reproductive-Health-and-Fertility/CF-and-the-Female-Reproductive-System/Fertility-in-Women-With-CF/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408809/

https://onlinelibrary.wiley.com/doi/abs/10.7863/jum.1983.2.10.439

https://thorax.bmj.com/content/56/8/649

https://www.cff.org/Life-With-CF/Transitions/Family-Planning-and-Parenting-With-CF/Alternative-Ways-to-Build-a-Family/Assisted-Reproduction-and-CF/

https://www.cff.org/Life-With-CF/Transitions/Family-Planning-and-Parenting-With-CF/Pregnancy-and-CF/